ISSN 1662-4009 (online)

ey0018.8-7 | Important for Clinical Practice | ESPEYB18

8.7. Targeted metabolomics as a tool in discriminating endocrine from primary hypertension

Z Erlic , P Reel , S Reel , L Amar , A Pecori , CK Larsen , M Tetti , C Pamporaki , C Prehn , J Adamski , A Prejbisz , F Ceccato , C Scaroni , M Kroiss , MC Dennedy , J Deinum , K Langton , P Mulatero , M Reincke , L Lenzini , AP Gimenez-Roqueplo , G Assie , A Blanchard , MC Zennaro , E Jefferson , F Beuschlein

J Clin Endocrinol Metab. 2021 Mar 25;106(4):1111–1128.https://pubmed.ncbi.nlm.nih.gov/33382876/In this multicentre patient cohort study, the authors investigated the use of targeted metabolomics to discriminate primary hypertension (PHT) from endocrine forms of hypertension (EHT). They identified 16 metabolites that help to discriminate between PHT and EHT.Arteri...

ey0016.15-1 | (1) | ESPEYB16

15.1. A Copeptin-based approach in the diagnosis of diabetes insipidus

W Fenske , J Refardt , I Chifu , I Schnyder , B Winzeler , J Drummond , A Jr. Ribeiro-Oliveira , T Drescher , S Bilz , DR Vogt , U Malzahn , M Kroiss , E Christ , C Henzen , S Fischli , A Tonjes , B Mueller , J Schopohl , J Flitsch , G Brabant , M Fassnacht , M Christ-Crain

To read the full abstract: N Engl J Med 2018;379:428–439In this multi-centre cohort of 156 patients with hypotonic polyuria, direct measurement of hypertonic saline-stimulated plasma copeptin had much greater diagnostic accuracy than a standard water-deprivation test, as judged by the final reference diagnosis, which was determined on the basis of medical history, test result...